Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.50 |
| ▸ | DRD3 | P35462 | 5/20 | 0.50 |
| ▸ | HRH2 | P25021 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098769 | 0.91 | DRD2 (0.53) | DRD2DRD3HRH2ADRA2ADRD4 | |
| SCHEMBL4425041 | 0.87 | DRD2 (0.52) | DRD2DRD3HRH2ADRA2ADRD4 | |
| SCHEMBL5810245 | 0.86 | DRD2 (0.59) | DRD2DRD3HRH2ADRA2ADRD4 | |
| SCHEMBL5810241 | 0.86 | DRD2 (0.59) | DRD2DRD3HRH2ADRA2ADRD4 | |
| SCHEMBL5810238 | 0.86 | DRD2 (0.59) | DRD2DRD3HRH2ADRA2ADRD4 | |
| Bromide SCHEMBL4429410 | 0.85 | DRD2 (0.51) | DRD2DRD3HRH2ADRA2ADRD4 | |
| Hydrochloric Acid SCHEMBL5809870 | 0.84 | ADRA2A (0.60) | DRD2DRD3HRH2ADRA2ADRD4 | |
| Hydrochloric Acid SCHEMBL5809875 | 0.84 | ADRA2A (0.60) | DRD2DRD3HRH2ADRA2ADRD4 | |
| Hydrochloric Acid SCHEMBL28039363 | 0.84 | ADRA2A (0.60) | DRD2DRD3HRH2ADRA2ADRD4 | |
| Hydrochloric Acid SCHEMBL5809871 | 0.84 | ADRA2A (0.60) | DRD2DRD3HRH2ADRA2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021214-A2 | IMPROVED PROCESS FOR THE PREPARATION OF (S)-2-AMINO-4,5,6,7-TETRAHYDRO-6 - (PROPYLAMINO) BENZOTHIAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | MSN LABORATORIES LIMITED (IN) | 2011-02-24 | — | — | WO | disclosed |