SCHEMBL6866833

SCHEMBL6866833

C[SiH](C)Cl.Cl[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
TSHR P16473 2/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9230901 0.89 TSHR (0.33) ESR1ESR2TSHR
Benzene SCHEMBL28553774 0.86 TSHR (0.39) ESR1ESR2TSHRLMNAALOX12
SCHEMBL38744 0.86 TSHR (0.39) ESR1ESR2TSHRLMNAALOX12
SCHEMBL23898214 0.83 ESR1 (0.42) ESR1ESR2TSHRLMNAALOX12
Methane SCHEMBL10789435 0.83 TSHR (0.37) ESR1ESR2TSHRLMNAALOX12
SCHEMBL27943171 0.83 TSHR (0.37) ESR1ESR2TSHRLMNAALOX12
Fluoride SCHEMBL28289678 0.83 TSHR (0.37) ESR1ESR2TSHRLMNAALOX12
SCHEMBL5065485 0.79 ESR1 (0.34) ESR1ESR2TSHRLMNAALOX12
SCHEMBL28518241 0.78 TSHR (0.33) ESR1ESR2TSHR
Chlorobenzene SCHEMBL28175808 0.76 TSHR (0.61) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6803427-B2 POLYMERIZATION IN PRESENCE OF A CATALYST OBTAINED BY REACTING HALO-MAGNESIUM WITH AN ALCOHOL, PRODUCT OF WHICH REACTS WITH A HYDROXY ESTER AND AN ALKOXYSILANE, AND FURTHER WITH A TITANIUM AND A SILICON COMPOUND SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2004-10-12 US claimed