SCHEMBL5065485

SCHEMBL5065485

C[SiH](Cl)Cl.Cl[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
TSHR P16473 2/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27676763 0.86 ESR1 (0.41) ESR1ESR2TSHRLMNAALOX12
Chloromethane SCHEMBL27870447 0.86 ESR1 (0.39) ESR1ESR2TSHRLMNAALOX12
Benzene SCHEMBL28183259 0.86 TSHR (0.39) ESR1ESR2TSHRLMNAALOX12
SCHEMBL76000 0.86 TSHR (0.39) ESR1ESR2TSHRLMNAALOX12
SCHEMBL29120692 0.86 TSHR (0.39) ESR1ESR2TSHRLMNAALOX12
Hydrochloric Acid SCHEMBL28179995 0.83 TSHR (0.37) ESR1ESR2TSHRLMNAALOX12
SCHEMBL705847 0.83 ESR1 (0.40) ESR1ESR2TSHRLMNAALOX12
Fluoride SCHEMBL5604818 0.83 TSHR (0.37) ESR1ESR2TSHRLMNAALOX12
SCHEMBL9359904 0.79 ESR1 (0.39) ESR1ESR2TSHRLMNAALOX12
Toluene SCHEMBL28546934 0.79 ACHE (0.58) ESR1ESR2TSHRLMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1958979-A1 POLYSILANE AND RESIN COMPOSITION CONTAINING POLYSILANE OSAKA GAS CO., LTD. (JP) 2008-08-20 EP disclosed