SCHEMBL38744

SCHEMBL38744

Cl[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
HSD17B10 Q99714 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MGLL Q99685 1/20 0.37
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 4/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
MAPK1 P28482 2/20 0.33
LMNA P02545 2/20 0.33
BBOX1 O75936 1/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ORAI1 Q96D31 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28553774 1.00 TSHR (0.39) TSHRHSD17B10MAPTHPGDSMN1; SMN2
Methane SCHEMBL10789435 0.97 TSHR (0.37) TSHRHSD17B10MAPTHPGDSMN1; SMN2
SCHEMBL9230901 0.91 TSHR (0.33) TSHRHSD17B10MAPTHPGDSMN1; SMN2
SCHEMBL23898214 0.91 ESR1 (0.42) TSHRHSD17B10MAPTHPGDSMN1; SMN2
SCHEMBL28518241 0.91 TSHR (0.33) TSHRHSD17B10MAPTHPGDSMN1; SMN2
SCHEMBL6047861 0.86 ALDH1A1 (0.30) TSHRALDH1A1TDP1ESR1ESR2
SCHEMBL6866833 0.86 ESR1 (0.34) TSHRESR1ESR2LMNAALOX12
SCHEMBL1941691 0.82 ALDH1A1 (0.50) HSD17B10SMN1; SMN2MGLLALDH1A1TDP1
SCHEMBL8979236 0.80 ESR1 (0.35) ESR1ESR2CA4
Ether SCHEMBL28930315 0.80 LTA4H (0.34) TSHRHPGDSMN1; SMN2ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12484 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095037-A Coating composition 2026-05-26 CN claimed
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same AXEED INC. (KR) 2026-05-05 US claimed
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
US-20260103820-A1 METHOD FOR PREPARING FULLERENE SINGLE-CRYSTAL FILMS AND USES FIELD OF TECHNOLOGY ZHEJIANG UNIVERSITY (CN) 2026-04-16 US claimed
US-20260047362-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-02-12 US claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
US-20250382477-A1 ANTIBACTERIAL THERMOPLASTIC SUBSTRATE GEHR KUNSTSTOFF EXTRUSIONSGESELLSCHAFT MBH (DE) 2025-12-18 US claimed
US-20250377336-A1 COATING INNER SURFACES OF ENCLOSED ARTICLES UNIV TASMANIA (AU) 2025-12-11 US claimed
EP-4588654-A1 COMPOSITE MATERIAL WITH ADHESION PROMOTER LAYER Carl Freudenberg KG (DE) 2025-07-23 EP claimed
CN-120157944-A Modified methyl silicone resin and preparation method thereof 山东东湖新材料有限公司 2025-06-17 CN claimed
US-4075367-A SEMICONDUCTOR PROCESSING OF SILICON NITRIDE NCR CORPORATION (US) 1978-02-21 US claimed
US-4068919-A POLYSILOXANES, WAVEGUIDES THOMSON-CSF (FR) 1978-01-17 US claimed
US-4066817-A SILANOL-CONTAINING ORGANOPOLYSILOXANE RESIN, FLUOROCARBON POLYMER THE DEXTER CORPORATION (US) 1978-01-03 US claimed
US-4061844-A AMINOALKYL ACRYLATE COPOLYMER, SILICON OR TIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-12-06 US claimed
US-4056488-A SYNTHETIC AMORPHOUS SILICAS OF PREDETERMINED PORE DISTRIBUTION, METHOD OF PRODUCING SAME MOBIL OIL CORPORATION (US) 1977-11-01 US claimed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US claimed
US-4028339-A UTENSILS GENERAL ELECTRIC COMPANY (US) 1977-06-07 US claimed
US-4003825-A CRACKING CATALYSTS MOBIL OIL CORPORATION (US) 1977-01-18 US claimed
US-3983055-A Synthetic amorphous silicas of predetermined pore distribution method of producing same MOBIL OIL CORPORATION (US) 1976-09-28 US claimed
US-3980686-A Process for the preparation of chlorosilane RHONE-POULENC INDUSTRIES (FR) 1976-09-14 US claimed