Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866911 | 1.00 | HDAC1 (0.42) | HDAC1HDAC6MCHR1ADRA2ANPY5R | |
| SCHEMBL6875886 | 0.89 | MCHR1 (0.42) | HDAC1HDAC6MCHR1ADRA2AADRA1A | |
| SCHEMBL6875769 | 0.89 | L3MBTL1 (0.45) | MCHR1ADRA2ANPY5RTAS2R14HTR1A | |
| SCHEMBL6875896 | 0.89 | MCHR1 (0.42) | HDAC1HDAC6MCHR1ADRA2AADRA1A | |
| SCHEMBL6875777 | 0.89 | L3MBTL1 (0.45) | MCHR1ADRA2ANPY5RTAS2R14HTR1A | |
| SCHEMBL6875905 | 0.89 | MCHR1 (0.42) | HDAC1HDAC6MCHR1ADRA2AADRA1A | |
| SCHEMBL6879134 | 0.88 | EHMT2 (0.38) | HDAC1HDAC6MCHR1ADRA2ANPY5R | |
| SCHEMBL6879138 | 0.88 | EHMT2 (0.38) | HDAC1HDAC6MCHR1ADRA2ANPY5R | |
| SCHEMBL6877568 | 0.87 | MCHR1 (0.38) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL6877577 | 0.87 | MCHR1 (0.38) | MCHR1ADRA2ANPY5RHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |