Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6875896 | 1.00 | MCHR1 (0.42) | MCHR1ADRA2AACHEBCHEKMT2A | |
| SCHEMBL6875886 | 1.00 | MCHR1 (0.42) | MCHR1ADRA2AACHEBCHEKMT2A | |
| SCHEMBL6866914 | 0.89 | HDAC1 (0.42) | MCHR1ADRA2AMAPK1HDAC1HDAC6 | |
| SCHEMBL6866911 | 0.89 | HDAC1 (0.42) | MCHR1ADRA2AMAPK1HDAC1HDAC6 | |
| SCHEMBL6868084 | 0.86 | MCHR1 (0.43) | MCHR1ADRA2AACHEBCHEKMT2A | |
| SCHEMBL6868077 | 0.86 | MCHR1 (0.43) | MCHR1ADRA2AACHEBCHEKMT2A | |
| SCHEMBL6868067 | 0.86 | MCHR1 (0.43) | MCHR1ADRA2AACHEBCHEKMT2A | |
| SCHEMBL6877327 | 0.83 | MCHR1 (0.35) | MCHR1ADRA2AHTTSMN1; SMN2 | |
| SCHEMBL6877335 | 0.83 | MCHR1 (0.35) | MCHR1ADRA2AHTTSMN1; SMN2 | |
| SCHEMBL6872959 | 0.82 | MCHR1 (0.40) | MCHR1ADRA2AACHEBCHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |