Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866079 | 0.93 | MEN1 (0.44) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL14359370 | 0.91 | POLB (0.53) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL8829446 | 0.87 | FAAH (0.53) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL8862703 | 0.85 | MGLL (0.52) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL1982535 | 0.85 | MGLL (0.52) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL8632299 | 0.85 | MGLL (0.52) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL8629340 | 0.85 | MGLL (0.52) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL8829438 | 0.85 | MGLL (0.52) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL8626070 | 0.85 | MGLL (0.52) | FAAHMGLLPOLBMEN1KMT2A | |
| SCHEMBL19233361 | 0.85 | MGLL (0.52) | FAAHMGLLPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013001498-A1 | AMIDOALKYLPIPERAZINYL DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | ADAMED SP. Z O.O. (PL) | 2013-01-03 | — | — | WO | disclosed |
| US-6812344-B1 | SYTHESIS OF COMPOUNDS FOR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | RANBAXY LABORATORIES LIMITED (IN) | 2004-11-02 | — | — | US | disclosed |
| US-6420366-B1 | PERIPHERAL VASCULAR DISEASE, CONGESTIVE HEART FAILURE, HYPERTENSION AND ESPECIALLY BENIGN PROSTATIC HYPERTROPHY. | RANBAXY LABORATORIES LIMITED (IN) | 2002-07-16 | — | — | US | disclosed |
| US-6420559-B1 | THE COMPOUNDS ARE USEFUL FOR TREATMENT OF DISEASE CONDITIONS, SUCH AS PERIPHERAL VASCULAR DISEASE, CONGESTIVE HEART FAILURE, HYPERTENSION AND ESPECIALLY BENIGN PROSTATIC HYPERTROPHY. | RANBAXY LABORATORIES LIMITED (IN) | 2002-07-16 | — | — | US | disclosed |
| US-6410735-B1 | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS; BENGIN PROSTATIC HYPERPLASIA | RANBAXY LABORATORIES LIMITED (IN) | 2002-06-25 | — | — | US | disclosed |
| US-6090809-A | 1-(4-arylpiperazin-1-yl)-ω-[n-(α..omega.-dicarboximido)]-alkanes useful as uro-selective α1 -adrenoceptor blockers | RANBAXY LABORATORIES LIMITED (IN) | 2000-07-18 | — | — | US | disclosed |
| US-6083950-A | TREATMENT OF PERIPHERAL VASCULAR DISEASE, CONGESTIVE HEART FAILURE, HYPERTENSION AND ESPECIALLY BENIGN PROSTATIC HYPERTROPHY | RANBAXY LABORATORIES LIMITED (IN) | 2000-07-04 | — | — | US | disclosed |