Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951867 | 0.86 | MAOB (0.48) | MAOBMAOACYP19A1CYP1A2CYP2D6 | |
| SCHEMBL957394 | 0.81 | MAOA (0.61) | MAOBMAOASIGMAR1CYP19A1TLR7 | |
| SCHEMBL3038687 | 0.81 | MAOA (0.61) | MAOBMAOASIGMAR1CYP19A1TLR7 | |
| SCHEMBL27263640 | 0.80 | CYP1A2 (0.58) | MAOBMAOASIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL11934786 | 0.79 | CYP19A1 (0.47) | MAOBMAOACYP19A1 | |
| SCHEMBL6675557 | 0.78 | MAOA (0.63) | MAOBMAOASIGMAR1CYP19A1BCHE | |
| SCHEMBL14931724 | 0.77 | MAOB (0.61) | MAOBMAOACYP19A1BCHE | |
| SCHEMBL29402451 | 0.76 | MAOA (0.59) | MAOBMAOASIGMAR1CYP19A1KCNH2 | |
| SCHEMBL292943 | 0.76 | MAOA (0.59) | MAOBMAOASIGMAR1CYP19A1KCNH2 | |
| Hydrochloric Acid SCHEMBL8396121 | 0.76 | MAOB (0.62) | MAOBMAOACYP19A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815445-B2 | FOR USE AS FLUORESCENCE DYES AND PROBES | Life Technologies Corporation | 2004-11-09 | — | — | US | disclosed |