SCHEMBL292943

SCHEMBL292943

CCCCCc1cccc(N)c1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.59
MAOB P27338 2/20 0.59
CYP19A1 P11511 1/20 0.57
LPL P06858 3/20 0.56
LIPG Q9Y5X9 3/20 0.56
TSHR P16473 1/20 0.51
SIGMAR1 Q99720 1/20 0.49
KCNH2 Q12809 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402451 1.00 MAOA (0.59) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL28489702 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL352479 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL28902509 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL9168076 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL6628922 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL3625874 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL29402837 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL16236477 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG
SCHEMBL29400049 0.98 LPL (0.57) MAOAMAOBCYP19A1LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117916657-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2024-04-19 CN claimed
US-20250179031-A1 PROTEASOME ENHANCERS AND USES THEREOF BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2025-06-05 US disclosed
CN-117940842-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2024-04-26 CN disclosed
CN-117916657-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2024-04-19 CN disclosed
US-20240068009-A1 SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES PROMEGA CORPORATION 2024-02-29 US disclosed
US-11781168-B2 Process for preparing substituted imidazo[1,2-α]pyrazines PROMEGA CORPORATION (US) 2023-10-10 US disclosed
CN-116868114-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2023-10-10 CN disclosed
WO-2023147485-A2 PROTEASOME ENHANCERS AND USES THEREOF BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2023-08-03 WO disclosed
WO-2023147485-A2 PROTEASOME ENHANCERS AND USES THEREOF BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2023-08-03 WO disclosed
US-20230159492-A1 FERROPTOSIS INHIBITORS - DIARYLAMINE PARA-ACETAMIDES Sironax Ltd. (KY) 2023-05-25 US disclosed
US-20030203817-A1 High-molecular weight gel and display device FUJI PHOTO FILM CO., LTD. 2003-10-30 US disclosed
CN-1357052-A Method for pretreating sample for cholesterol quantification and method for quantifying cholesterol in specific lipoprotein by using same DAIICHI PURE CHEMICALS CO LTD (JP) 2002-07-03 CN disclosed
CN-1344371-A Method for quantitating cholesterol DAIICHI PURE CHEMIALS CO LTD (JP) 2002-04-10 CN disclosed
CN-1268185-A Method for quantitating high density lipoprotein cholesterol DAIICHI PURE CHEMICALS CO LTD (JP) 2000-09-27 CN disclosed
US-5086052-A Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis ABBOTT LABORATORIES (US) 1992-02-04 US disclosed
US-4970210-A ENZYME INHIBITORS ABBOTT LABORATORIES (US) 1990-11-13 US disclosed
EP-0299449-A2 Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds ABBOTT LABORATORIES (US) 1989-01-18 EP disclosed
EP-0205272-A2 Cinnoline derivatives ICI AMERICAS INC. (US) 1986-12-17 EP disclosed
US-4134917-A Method for the denitrosation of organic nitrosamines AMERICAN CYANAMID COMPANY (US) 1979-01-16 US disclosed
US-4062952-A Substituted benzenedisulfonamides as anthelmintics MERCK & CO., INC. (US) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179031-A1 PROTEASOME ENHANCERS AND USES THEREOF PSME3, PSMG3, PSME1 MAOA 1602/4885MAOB 1646/4885CYP19A1 3443/4885
US-11781168-B2 Process for preparing substituted imidazo[1,2-α]pyrazines CYP4Z1, CYP2E1, CYP2F1 MAOA 1131/4885MAOB 950/4885CYP19A1 344/4885
US-20240068009-A1 SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES PGLS, AADAC, GLB1 MAOA 3294/4885MAOB 3130/4885CYP19A1 2106/4885
US-20230159492-A1 FERROPTOSIS INHIBITORS - DIARYLAMINE PARA-ACETAMIDES AIFM2, FECH, GPX4 MAOA 3630/4885MAOB 3452/4885CYP19A1 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.