SCHEMBL686758

SCHEMBL686758

Cc1cc(C(C)(C)c2ccc(C(C)(C)c3cc(C)c(O)c(C)c3)cc2)cc(C)c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.60
ESR2 Q92731 6/20 0.56
CYP3A4 P08684 3/20 0.56
HPGD P15428 3/20 0.56
HSD17B10 Q99714 3/20 0.56
TSHR P16473 2/20 0.56
AR P10275 2/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
HTR6 P50406 1/20 0.56
ESRRG P62508 1/20 0.56
SLC6A3 Q01959 1/20 0.56
ALOX15 P16050 4/20 0.50
ALDH1A1 P00352 4/20 0.50
ALOX12 P18054 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CASP1 P29466 1/20 0.50
RECQL P46063 1/20 0.50
HIF1A Q16665 1/20 0.50
CA1 P00915 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728306 0.93 ESR1 (0.70) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL15625206 0.93 ESR1 (0.54) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL69586 0.92 ALDH1A1 (0.56) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL2314239 0.91 ESR1 (0.52) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL29472991 0.90 ALDH1A1 (0.54) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL2618674 0.90 ALDH1A1 (0.54) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL1023357 0.89 ESR1 (0.59) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL30607257 0.87 ESR1 (0.83) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL726372 0.87 ESR1 (0.83) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL12299305 0.86 ESR1 (0.47) ESR1ESR2CYP3A4HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 757 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4801308-B2 2011-10-26 JP claimed
EP-2344927-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2011-07-20 EP claimed
WO-2010043946-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-04-22 WO claimed
US-20090081589-A1 THICK FILM RESISTS MERCK PATENT GMBH (DE) 2009-03-26 US claimed
EP-1569795-B1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEM CO (US) 2008-09-03 EP claimed
EP-1575774-B1 ARTICLES OF MANUFACTURE INCORPORATING POLYESTER/POLYCARBONATE BLENDS EASTMAN CHEM CO (US) 2008-08-13 EP claimed
US-7118799-B2 Thermoplastic article having a decorative material embedded therein EASTMAN CHEMICAL COMPANY (US) 2006-10-10 US claimed
EP-1575774-A1 ARTICLES OF MANUFACTURE INCORPORATING POLYESTER/POLYCARBONATE BLENDS EASTMAN CHEMICAL COMPANY (US) 2005-09-21 EP claimed
US-6905809-B2 Photoresist compositions CLARIANT FINANCE (BVI) LIMITED (VG) 2005-06-14 US claimed
EP-1274781-B1 POLYCARBONATE COMPOSITION RESISTANT TO GAMMA RADIATION BAYER AG (US) 2004-12-15 EP claimed
EP-0326177-B1 Epoxy resin composition and prepreg for composite materials using the same MITSUBISHI RAYON CO (JP) 1995-01-18 EP claimed
US-5342905-A Process for making an ester containing polyether sulfone MILES INC. (US) 1994-08-30 US claimed
US-4959438-A Epoxy resin composition and prepreg for composite materials using the same from bi and tri-epoxides, triarylbisphenols and diaminodiphenylsulfones MITSUBISHI RAYON COMPANY, LTD. (JP) 1990-09-25 US claimed
EP-0326177-A2 Epoxy resin composition and prepreg for composite materials using the same MITSUBISHI RAYON COMPANY, LTD. (JP) 1989-08-02 EP claimed
EP-0093914-B2 PROCESS FOR THE PRODUCTION OF POLYCARBONATE IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-04-19 EP claimed
US-4452966-A REACTING A POLYCARBONATE OLIGOMER WITH A THREE FUNCTIONAL GROUP COMPOUND, THEN A DIHYDRIC PHENOL IDEMITSU KOSAN COMPANY LIMITED (JP) 1984-06-05 US claimed
EP-0093914-A1 Process for the production of polycarbonate IDEMITSU KOSAN COMPANY LIMITED (JP) 1983-11-16 EP claimed
US-4172103-A MIXTURE WITH THERMOPLASTIC ADDITION POLYMER; IMPACT STRENGTH; CHEMICAL RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1979-10-23 US claimed
US-4100130-A Flame-resistant polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1978-07-11 US claimed
US-4005037-A Polycarbonate-polyvinyl chloride moulding compounds BAYER AKTIENGESELLSCHAFT (DT) 1977-01-25 US claimed