SCHEMBL726372

SCHEMBL726372

Cc1cc(C(C)(C)c2cc(C)c(O)c(C)c2)ccc1O

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.83
ALOX15 P16050 3/20 0.56
ALOX12 P18054 2/20 0.56
ESR2 Q92731 8/20 0.53
AR P10275 4/20 0.53
KLF10 Q13118 1/20 0.50
TDP1 Q9NUW8 3/20 0.46
TP53 P04637 1/20 0.46
RORC P51449 1/20 0.46
HPGD P15428 3/20 0.43
HSD17B10 Q99714 3/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
CASP1 P29466 1/20 0.43
RECQL P46063 1/20 0.43
HIF1A Q16665 1/20 0.43
PDE10A Q9Y233 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30607257 1.00 ESR1 (0.83) ESR1ALOX15ALOX12ESR2AR
SCHEMBL1416326 0.93 ESR1 (0.71) ESR1ALOX15ALOX12ESR2AR
SCHEMBL10935934 0.93 ESR1 (0.71) ESR1ALOX15ALOX12ESR2AR
SCHEMBL3913903 0.91 ESR1 (0.91) ESR1ALOX15ALOX12ESR2AR
SCHEMBL29350788 0.91 ESR1 (1.00) ESR1ALOX15ALOX12ESR2AR
SCHEMBL29360146 0.91 ESR1 (1.00) ESR1ALOX15ALOX12ESR2AR
SCHEMBL35285 0.91 ESR1 (1.00) ESR1ALOX15ALOX12ESR2AR
SCHEMBL29696084 0.89 ESR1 (0.95) ESR1ALOX15ALOX12ESR2AR
SCHEMBL298974 0.89 ESR1 (0.95) ESR1ALOX15ALOX12ESR2AR
SCHEMBL30606308 0.89 ESR1 (0.66) ESR1ALOX15ALOX12ESR2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12215189-B2 Bisphenol composition and polycarbonate resin MITSUBISHI CHEMICAL CORPORATION (JP) 2025-02-04 US claimed
CN-113574042-B Bisphenol composition and polycarbonate resin 三菱化学株式会社 2023-10-13 CN claimed
EP-3939957-A1 BISPHENOL COMPOSITION AND POLYCARBONATE RESIN Mitsubishi Chemical Corporation (JP) 2022-01-19 EP claimed
US-20210403641-A1 BISPHENOL COMPOSITION AND POLYCARBONATE RESIN MITSUBISHI CHEMICAL CORPORATION (JP) 2021-12-30 US claimed
CN-113574042-A Bisphenol composition and polycarbonate resin 三菱化学株式会社 2021-10-29 CN claimed
WO-2020184183-A1 BISPHENOL COMPOSITION AND POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-17 WO claimed
EP-1660560-B1 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
CN-103497334-A Copolyetherimides SABIC INNOVATIVE PLASTICS IP 2014-01-08 CN claimed
CN-1938379-B Impact-modified compositions and methods GEN ELECTRIC 2012-05-16 CN claimed
JP-4768635-B2 2011-09-07 JP claimed
WO-2005021477-A2 METHOD FOR MAKING SALTS OF HYDROXY-SUBSTITUTED HYDROCARBONS GENERAL ELECTRIC COMPANY (US) 2005-03-10 WO claimed
US-20050049390-A1 Phase transfer catalyzed method for preparation of polyetherimides GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-20050049439-A1 Method for making salts hydroxy-substituted hydrocarbons GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-6849706-B1 Copolyetherimides GENERAL ELECTRIC COMPANY (US) 2005-02-01 US claimed
US-6844071-B1 Multilayer articles comprising polycarbonate and polypropylene and method for their preparation GENERAL ELECTRIC COMPANY (US) 2005-01-18 US claimed
US-6713598-B2 FLAME RETARDANT WITH SPECIFIED MOLECULAR WEIGHT AND SOFTENING TEMPERATURE; REACTING PHOSPHORUS OXYHALIDE WITH HYDROXYAROMATIC COMPOUND, REACTING ARYLDIHALOPHOSPHATE WITH DIHYDROXYAROMATIC, THEN WITH HYDROXYAROMATIC GENERAL ELECTRIC COMPANY 2004-03-30 US claimed
US-20040044134-A1 METHOD TO MAKE A SOLID POLYMERIC PHOSPHATE AND RESINOUS COMPOSITIONS CONTAINING IT GENERAL ELECTRIC COMPANY 2004-03-04 US claimed
WO-2004016685-A2 FLAME RETARDANT RESINOUS COMPOSITIONS AND METHOD GENERAL ELECTRIC COMPANY (US) 2004-02-26 WO claimed
US-20040034132-A1 Flame retardant resinous compositions and method GENERAL ELECTRIC COMPANY 2004-02-19 US claimed
US-20040014934-A1 Method for the production of polyestercarbonates GENERAL ELECTRIC COMPANY 2004-01-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215189-B2 Bisphenol composition and polycarbonate resin SUZ12, RB1, RRP12 ESR1 71/4885ALOX15 1593/4885ALOX12 467/4885
US-20050049439-A1 Method for making salts hydroxy-substituted hydrocarbons HDHD5, SHH, HAAO ESR1 2614/4885ALOX15 496/4885ALOX12 676/4885
US-20210403641-A1 BISPHENOL COMPOSITION AND POLYCARBONATE RESIN SUZ12, RB1, RRP12 ESR1 71/4885ALOX15 1593/4885ALOX12 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.