Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867771 | 1.00 | TNNC1 (0.48) | TNNC1FAAHMAPTTRPV1NAAA | |
| SCHEMBL29187193 | 1.00 | TNNC1 (0.48) | TNNC1FAAHMAPTTRPV1NAAA | |
| SCHEMBL10985105 | 1.00 | TNNC1 (0.48) | TNNC1FAAHMAPTTRPV1NAAA | |
| SCHEMBL10985108 | 1.00 | TNNC1 (0.48) | TNNC1FAAHMAPTTRPV1NAAA | |
| SCHEMBL27657994 | 0.92 | SMN1; SMN2 (0.41) | TNNC1FAAHMAPTNPC1RAB9A | |
| SCHEMBL154863 | 0.84 | NPC1 (0.44) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL154865 | 0.84 | NPC1 (0.44) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6046924 | 0.84 | TNNC1 (0.55) | TNNC1FAAHTRPV1 | |
| SCHEMBL11145609 | 0.83 | TBXAS1 (0.43) | TNNC1FAAHMAPTNPC1RAB9A | |
| SCHEMBL8200117 | 0.81 | MAPT (0.49) | FAAHMAPTNAAANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383745-A1 | CATIONIC AMPHIPHILES AS TRANSFECTION VEHICLES | Applied NanoSystems B.V. (NL) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090329-A1 | CATIONIC AMPHIPHILES AS TRANSFECTION VEHICLES | APPLIED NANOSYSTEMS B.V. (NL) | 2002-11-14 | — | — | WO | disclosed |