SCHEMBL6867906

SCHEMBL6867906

N#Cc1ccccc1Oc1cccc(Br)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
GAA P10253 1/20 0.54
FNTA P49354 1/20 0.51
FNTB P49356 1/20 0.51
PGGT1B P53609 1/20 0.51
AR P10275 8/20 0.47
PDE4A P27815 1/20 0.46
PDE4B Q07343 1/20 0.46
PDE4C Q08493 1/20 0.46
PDE4D Q08499 1/20 0.46
LRRK2 Q5S007 1/20 0.44
ALDH1A1 P00352 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP19A1 P11511 1/20 0.43
EGFR P00533 2/20 0.40
MAOB P27338 1/20 0.40
MAPK14 Q16539 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17752288 0.87 FNTA (0.57) FNTAFNTBPGGT1BARALDH1A1
SCHEMBL3841259 0.82 MAOB (0.50) GAAALDH1A1SMN1; SMN2EGFRMAOB
SCHEMBL26936308 0.81 ALDH1A1 (0.49) POLBGAAFNTAFNTBPGGT1B
SCHEMBL6871605 0.81 POLB (0.69) POLBGAAARPDE4APDE4B
SCHEMBL26936315 0.81 FNTA (0.49) POLBGAAFNTAFNTBPGGT1B
SCHEMBL30426714 0.80 AR (0.66) POLBGAAARPDE4APDE4B
SCHEMBL22868020 0.80 POLB (0.54) POLBGAAFNTAFNTBPGGT1B
SCHEMBL6511189 0.80 MAOB (0.55) POLBGAAARPDE4APDE4B
SCHEMBL8561327 0.80 POLB (0.73) POLBGAAFNTAFNTBPGGT1B
SCHEMBL7486810 0.80 POLB (0.54) POLBGAAARPDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113582908-A Near-ultraviolet organic electroluminescent material based on benzene cyano, preparation method thereof and application thereof in preparing OLED 华南理工大学 2021-11-02 CN claimed
CN-113582908-B Near-ultraviolet organic electroluminescent material based on phenylcyano, preparation method thereof and application thereof in OLED preparation 华南理工大学 2023-09-26 CN disclosed
CN-113582908-A Near-ultraviolet organic electroluminescent material based on benzene cyano, preparation method thereof and application thereof in preparing OLED 华南理工大学 2021-11-02 CN disclosed
US-6713474-B2 SERINE-THREONINE AND TYROSINE KINASE INHIBITORS ABBOTT GMBH & CO. KG (DE) 2004-03-30 US disclosed
US-20030153752-A1 Pyrrolopyrimidines as therapeutic agents ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2003-08-14 US disclosed
WO-2001072751-A1 PYRROLOPYRIMIDINES AS TYROSINE KINASE INHIBITORS KNOLL GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2001-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153752-A1 Pyrrolopyrimidines as therapeutic agents FLT1, FLT4, TFPI POLB 1457/4885GAA 4375/4885FNTA 2464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.