Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diaminooctane SCHEMBL6865639 | 0.97 | SIGMAR1 (0.58) | SIGMAR1DNM1CA12CA1CA2 | |
| Diaminooctane SCHEMBL6859282 | 0.97 | SIGMAR1 (0.58) | SIGMAR1DNM1CA12CA1CA2 | |
| Cyclohexylamine SCHEMBL28057105 | 0.97 | SIGMAR1 (0.58) | SIGMAR1DNM1CA12CA1CA2 | |
| Diaminooctane SCHEMBL6865074 | 0.97 | SIGMAR1 (0.58) | SIGMAR1DNM1CA12CA1CA2 | |
| Diaminooctane SCHEMBL6865790 | 0.97 | SIGMAR1 (0.58) | SIGMAR1DNM1CA12CA1CA2 | |
| Cyclopentanamine SCHEMBL20298276 | 0.88 | DNM1 (0.59) | SIGMAR1DNM1TSHRMEN1KMT2A | |
| SCHEMBL9844538 | 0.88 | DNM1 (0.53) | SIGMAR1DNM1CA12CA1CA2 | |
| Cyclohexylamine SCHEMBL6865558 | 0.86 | DNM1 (0.56) | SIGMAR1DNM1TSHRMEN1KMT2A | |
| Cyclohexylamine SCHEMBL3138481 | 0.86 | DNM1 (0.56) | SIGMAR1DNM1TSHRMEN1KMT2A | |
| Decylamine SCHEMBL3259417 | 0.86 | DNM1 (0.56) | SIGMAR1DNM1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |