Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868414 | 1.00 | MCHR1 (0.39) | MCHR1ADRA2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6876555 | 0.88 | MCHR1 (0.42) | MCHR1ADRA2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6876552 | 0.88 | MCHR1 (0.42) | MCHR1ADRA2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6876993 | 0.83 | MCHR1 (0.44) | MCHR1ADRA2ALMNAL3MBTL1GAA | |
| SCHEMBL6876997 | 0.83 | MCHR1 (0.44) | MCHR1ADRA2ALMNAL3MBTL1GAA | |
| SCHEMBL6878174 | 0.83 | MCHR1 (0.43) | MCHR1ADRA2AL3MBTL1ALDH1A1BCHE | |
| SCHEMBL6466543 | 0.83 | MCHR1 (0.43) | MCHR1ADRA2AL3MBTL1ALDH1A1BCHE | |
| SCHEMBL6461843 | 0.81 | MCHR1 (0.60) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL6457644 | 0.81 | MCHR1 (0.59) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6456988 | 0.80 | MCHR1 (0.57) | MCHR1ADRA2AALDH1A1HTTHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |