Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876997 | 1.00 | MCHR1 (0.44) | MCHR1ADRA2ABCHEACHELMNA | |
| SCHEMBL6876580 | 0.83 | MCHR1 (0.43) | MCHR1ADRA2AACHELMNAL3MBTL1 | |
| SCHEMBL6876575 | 0.83 | MCHR1 (0.43) | MCHR1ADRA2AACHELMNAL3MBTL1 | |
| SCHEMBL6868411 | 0.83 | MCHR1 (0.39) | MCHR1ADRA2ABCHEACHELMNA | |
| SCHEMBL6868414 | 0.83 | MCHR1 (0.39) | MCHR1ADRA2ABCHEACHELMNA | |
| SCHEMBL13795246 | 0.82 | MCHR1 (0.65) | MCHR1ADRA2ABCHEACHEHRH1 | |
| SCHEMBL6875977 | 0.81 | ALOX12 (0.56) | MCHR1ADRA2ALMNANPC1RAB9A | |
| SCHEMBL6875980 | 0.81 | ALOX12 (0.56) | MCHR1ADRA2ALMNANPC1RAB9A | |
| SCHEMBL6466543 | 0.81 | MCHR1 (0.43) | MCHR1ADRA2ABCHEACHEL3MBTL1 | |
| SCHEMBL6878174 | 0.81 | MCHR1 (0.43) | MCHR1ADRA2ABCHEACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |