Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868480 | 1.00 | MCHR1 (0.44) | MCHR1ADRA2AEPHX1ACP1HTR1A | |
| SCHEMBL6464772 | 0.90 | MCHR1 (0.41) | MCHR1ADRA2AACP1NPY5REPHX2 | |
| SCHEMBL6459092 | 0.90 | MCHR1 (0.41) | MCHR1ADRA2AACP1NPY5REPHX2 | |
| SCHEMBL6874728 | 0.89 | LCK (0.49) | MCHR1ADRA2AEPHX1LCK | |
| SCHEMBL6874723 | 0.89 | LCK (0.49) | MCHR1ADRA2AEPHX1LCK | |
| SCHEMBL6876607 | 0.88 | ACP1 (0.47) | MCHR1ADRA2AEPHX1ACP1HTR1A | |
| SCHEMBL6876600 | 0.88 | ACP1 (0.47) | MCHR1ADRA2AEPHX1ACP1HTR1A | |
| SCHEMBL6868935 | 0.88 | EPHX1 (0.47) | MCHR1ADRA2AEPHX1HTR1AADRA1A | |
| SCHEMBL6868939 | 0.88 | EPHX1 (0.47) | MCHR1ADRA2AEPHX1HTR1AADRA1A | |
| SCHEMBL6456407 | 0.86 | EPHX1 (0.47) | MCHR1ADRA2AEPHX1HTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |