Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 14/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868939 | 1.00 | EPHX1 (0.47) | EPHX1MCHR1ADRA2AKDM4ELMNA | |
| SCHEMBL6456415 | 0.91 | EPHX1 (0.47) | EPHX1MCHR1ADRA2AKDM4ELMNA | |
| SCHEMBL6456407 | 0.91 | EPHX1 (0.47) | EPHX1MCHR1ADRA2AKDM4ELMNA | |
| SCHEMBL6874728 | 0.88 | LCK (0.49) | EPHX1MCHR1ADRA2AKDM4ELMNA | |
| SCHEMBL6874723 | 0.88 | LCK (0.49) | EPHX1MCHR1ADRA2AKDM4ELMNA | |
| SCHEMBL6868480 | 0.88 | MCHR1 (0.44) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6868474 | 0.88 | MCHR1 (0.44) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6462318 | 0.88 | RAB9A (0.50) | EPHX1MCHR1ADRA2ASMN1; SMN2RAB9A | |
| SCHEMBL6462316 | 0.88 | RAB9A (0.50) | EPHX1MCHR1ADRA2ASMN1; SMN2RAB9A | |
| SCHEMBL6877843 | 0.87 | EPHX1 (0.49) | EPHX1MCHR1ADRA2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |