Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.40 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877596 | 1.00 | ACHE (0.40) | ACHEBCHEDRD2MCHR1ADRA2A | |
| SCHEMBL6868494 | 1.00 | ACHE (0.40) | ACHEBCHEDRD2MCHR1ADRA2A | |
| SCHEMBL6877600 | 1.00 | ACHE (0.40) | ACHEBCHEDRD2MCHR1ADRA2A | |
| SCHEMBL6876356 | 0.90 | ACHE (0.41) | ACHEBCHEMCHR1ADRA2A | |
| SCHEMBL6876358 | 0.90 | ACHE (0.41) | ACHEBCHEMCHR1ADRA2A | |
| SCHEMBL6872959 | 0.88 | MCHR1 (0.40) | ACHEBCHEMCHR1ADRA2ACTSS | |
| SCHEMBL6872955 | 0.88 | MCHR1 (0.40) | ACHEBCHEMCHR1ADRA2ACTSS | |
| SCHEMBL6880014 | 0.86 | MCHR1 (0.41) | ACHEMCHR1ADRA2ANPY5R | |
| SCHEMBL6880020 | 0.86 | MCHR1 (0.41) | ACHEMCHR1ADRA2ANPY5R | |
| SCHEMBL6876552 | 0.85 | MCHR1 (0.42) | MCHR1ADRA2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |