Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868526 | 1.00 | MCHR1 (0.46) | MCHR1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL6879021 | 0.90 | MCHR1 (0.45) | MCHR1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL6879024 | 0.90 | MCHR1 (0.45) | MCHR1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL6876071 | 0.87 | KMT2A (0.48) | MCHR1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL6876075 | 0.87 | KMT2A (0.48) | MCHR1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL27653033 | 0.86 | SIGMAR1 (0.50) | MCHR1LMNAKDM4ESMN1; SMN2ADRA2A | |
| SCHEMBL6873492 | 0.85 | ALOX12 (0.55) | MCHR1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6873494 | 0.85 | ALOX12 (0.55) | MCHR1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6866938 | 0.85 | MCHR1 (0.55) | MCHR1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL6866944 | 0.85 | MCHR1 (0.55) | MCHR1MEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |