SCHEMBL6868699

SCHEMBL6868699

Cc1ccc(C(=O)Oc2ccc(C(=O)O)c(-c3ccccc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
MAPT P10636 3/20 0.47
MEN1 O00255 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CA9 Q16790 1/20 0.46
GBA1 P04062 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
LMNA P02545 1/20 0.44
AKR1C3 P42330 1/20 0.44
PRSS1 P07477 1/20 0.44
ACR P10323 1/20 0.44
NPC1 O15118 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6870295 0.90 KMT2A (0.57) KMT2AMAPTMEN1TDP1CA9
SCHEMBL9682972 0.90 KMT2A (0.44) KMT2AMAPTMEN1TDP1GBA1
SCHEMBL30073152 0.88 PRSS1 (0.48) KMT2AMAPTMEN1GBA1HDAC7
SCHEMBL10526606 0.86 MAPT (0.53) KMT2AMAPTMEN1TDP1CA9
SCHEMBL6868696 0.85 NPC1 (0.53) KMT2AMAPTTDP1GAAAKR1C3
SCHEMBL6865768 0.82 KMT2A (0.54) KMT2AMAPTMEN1CYP1A2CYP2C19
SCHEMBL10479949 0.80 BACE1 (0.64) KMT2AMAPTMEN1TDP1GAA
SCHEMBL13415307 0.79 SMN1; SMN2 (0.58) KMT2AMAPTMEN1TDP1CYP1A2
SCHEMBL13177239 0.79 SMN1; SMN2 (0.58) KMT2AMAPTMEN1TDP1CYP1A2
SCHEMBL11761669 0.79 SMN1; SMN2 (0.58) KMT2AMAPTMEN1TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720287-B2 WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED FUJI PHOTO FILM CO., LTD. (JP) 2004-04-13 US disclosed
US-20030045426-A1 Heat sensitive recording material and microcapsule solution FUJI PHOTO FILM CO., LTD. 2003-03-06 US disclosed