Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868699 | 0.90 | KMT2A (0.47) | KMT2AGBA1GAAHPGDLMNA | |
| SCHEMBL30073152 | 0.88 | PRSS1 (0.48) | KMT2AGBA1GAAHPGDLMNA | |
| SCHEMBL28692920 | 0.87 | HSD17B10 (0.51) | KMT2AESR1ESR2HSD17B10MEN1 | |
| SCHEMBL31402588 | 0.87 | HSD17B10 (0.51) | KMT2AESR1ESR2HSD17B10MEN1 | |
| SCHEMBL13039041 | 0.84 | HSD17B1 (0.51) | KMT2AGBA1ESR1GAAHPGD | |
| SCHEMBL13039039 | 0.81 | KMT2A (0.54) | KMT2AGBA1ESR1ESR2GAA | |
| SCHEMBL8338448 | 0.81 | HCRTR1 (0.47) | KMT2AESR1HSD17B10HPGDLMNA | |
| SCHEMBL19726963 | 0.80 | PRSS1 (0.56) | KMT2AGBA1ESR1ESR2LMNA | |
| SCHEMBL16372985 | 0.80 | PRSS1 (0.56) | KMT2AGBA1ESR1ESR2LMNA | |
| SCHEMBL13039037 | 0.80 | PRSS1 (0.56) | KMT2AGBA1ESR1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0354347-A2 | Liquid crystal compounds,their manufacture as modifiers for polycarbonates,polyestercarbonates and polyesters | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |