Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.31 |
| ▸ | ITGAV | P06756 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688281 | 0.95 | KMT2A (0.36) | KMT2AMEN1HPGDLMNAFFAR1 | |
| SCHEMBL688737 | 0.94 | FFAR1 (0.36) | KMT2AMEN1FFAR1 | |
| SCHEMBL686618 | 0.93 | KMT2A (0.37) | KMT2AMEN1HPGDLMNAFFAR1 | |
| SCHEMBL687969 | 0.90 | CTSA (0.36) | KMT2AMEN1HPGDLMNAHSD17B10 | |
| SCHEMBL687858 | 0.90 | MEN1 (0.37) | KMT2AMEN1HPGDLMNAFFAR1 | |
| SCHEMBL686692 | 0.89 | SMN1; SMN2 (0.36) | KMT2AMEN1HPGDLMNAFFAR1 | |
| SCHEMBL687167 | 0.89 | KMT2A (0.37) | KMT2AMEN1HPGDLMNAFFAR1 | |
| SCHEMBL688414 | 0.89 | KMT2A (0.37) | KMT2AMEN1HPGDLMNAFFAR1 | |
| SCHEMBL688603 | 0.88 | KMT2A (0.36) | KMT2AMEN1HPGDLMNAFFAR1 | |
| SCHEMBL686894 | 0.88 | FFAR1 (0.38) | KMT2AMEN1FFAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |