Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686877 | 0.94 | KMT2A (0.36) | FFAR1MEN1KMT2A | |
| SCHEMBL686894 | 0.94 | FFAR1 (0.38) | FFAR1CTSAMEN1KMT2ACHRM3 | |
| SCHEMBL688281 | 0.91 | KMT2A (0.36) | FFAR1MEN1KMT2A | |
| SCHEMBL688783 | 0.89 | CTSA (0.38) | FFAR1CTSAMEN1KMT2ACHRM3 | |
| SCHEMBL686618 | 0.88 | KMT2A (0.37) | FFAR1MEN1KMT2A | |
| SCHEMBL686619 | 0.86 | KMT2A (0.35) | FFAR1MEN1KMT2A | |
| SCHEMBL688324 | 0.86 | MEN1 (0.39) | FFAR1CTSAMEN1KMT2ACHRM3 | |
| SCHEMBL687969 | 0.86 | CTSA (0.36) | CTSAMEN1KMT2AACACB | |
| SCHEMBL686692 | 0.85 | SMN1; SMN2 (0.36) | FFAR1MEN1KMT2A | |
| SCHEMBL688359 | 0.85 | KMT2A (0.35) | FFAR1MEN1KMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |