Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 11/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687480 | 0.92 | CTSA (0.36) | CTSAP2RX3LMNAHPGDHSD17B10 | |
| SCHEMBL686877 | 0.90 | KMT2A (0.36) | LMNAHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL688281 | 0.88 | KMT2A (0.36) | P2RX3LMNAHPGDHSD17B10MEN1 | |
| SCHEMBL686719 | 0.86 | MEN1 (0.38) | LMNAHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL688737 | 0.86 | FFAR1 (0.36) | CTSAMEN1KMT2AACACB | |
| SCHEMBL687500 | 0.85 | SMN1; SMN2 (0.37) | LMNAHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL687910 | 0.85 | MEN1 (0.39) | CTSALMNAHPGDKEAP1NFE2L2 | |
| SCHEMBL687908 | 0.84 | CTSA (0.38) | CTSAHPGDKEAP1NFE2L2MEN1 | |
| SCHEMBL687992 | 0.83 | KMT2A (0.44) | CTSALMNAHPGDKEAP1NFE2L2 | |
| SCHEMBL686618 | 0.82 | KMT2A (0.37) | LMNAHPGDHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |