Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9065393 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL815087 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL6661681 | 0.82 | CYP19A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL813802 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8652354 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL816104 | 0.80 | — | — | |
| SCHEMBL7946040 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL452746 | 0.79 | — | — | |
| SCHEMBL7938325 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL814303 | 0.78 | CES2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095081-B1 | POLYOLEFIN PRODUCTION | ATOFINA RES (BE) | 2004-09-29 | — | — | EP | disclosed |
| US-6265503-B1 | POLYPROPYLENE BLOCK POLYMER | FINA RESEARCH, S.A. (BE) | 2001-07-24 | — | — | US | disclosed |
| US-6245870-B1 | INTRODUCING SELECTED METALLOCENE CATALYST AND ALUMOXANE COCATALYST INTO POLYMERIZATION REACTION ZONE CONTAINING OLEFIN MONOMER, MAINTAINING REACTION ZONE UNDER POLYMERIZATION REACTION CONDITIONS, EXTRACTING SYNDIOTACTIC/ISOTACTIC BLOCK | FINA TECHNOLOGY, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6184318-B1 | METALLOCENE COMPOUND FOR USE AS CATALYST COMPONENT IN PRODUCTION OF SHORT SEQUENCE SYNDIOTACTIC/ISOTACTIC BLOCK POLYOLEFINS | FINA RESEARCH, S.A. (BE) | 2001-02-06 | — | — | US | disclosed |
| EP-0747406-B1 | Process for producing syndiotactic/isotactic block polyolefins | FINA TECHNOLOGY (US) | 1998-10-07 | — | — | EP | disclosed |
| EP-0747406-A1 | Process for producing syndiotactic/isotactic block polyolefins | FINA TECHNOLOGY, INC. (US) | 1996-12-11 | — | — | EP | disclosed |