SCHEMBL6869020

SCHEMBL6869020

O=C(Cc1ccccc1)Oc1ccccc1-c1ccccc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.50
PTGER1 P34995 2/20 0.49
KDM4E B2RXH2 6/20 0.48
MEN1 O00255 1/20 0.48
RECQL P46063 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
TSHR P16473 2/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
FOLH1 Q04609 1/20 0.46
HSD17B10 Q99714 5/20 0.46
HPGD P15428 3/20 0.46
ALDH1A1 P00352 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ATM Q13315 1/20 0.46
ESR1 P03372 1/20 0.45
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
HMGB1 P09429 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1358287 0.88 KDM4E (0.59) MAPK1KDM4EMEN1RECQLKMT2A
SCHEMBL10573912 0.82 MAPK1 (0.61) MAPK1KMT2ASMN1; SMN2TSHRHPGD
SCHEMBL6257888 0.81 KDM4E (0.52) MAPK1PTGER1KDM4EKMT2ATSHR
SCHEMBL6847069 0.81 MAPK1 (0.50) MAPK1KDM4EMEN1RECQLKMT2A
SCHEMBL11622076 0.80 MAPK1 (0.52) MAPK1KDM4EMEN1RECQLKMT2A
SCHEMBL27658575 0.79 SLC6A3 (0.62) MAPK1KDM4EMEN1RECQLKMT2A
SCHEMBL9138776 0.78 KDM4E (0.73) MAPK1PTGER1KDM4EMEN1KMT2A
SCHEMBL6883400 0.78 KDM4E (0.72) KDM4EMEN1RECQLKMT2ATSHR
SCHEMBL5483055 0.77 GAA (0.53) MAPK1MEN1KMT2ASMN1; SMN2TSHR
SCHEMBL6870248 0.77 SLC6A3 (0.63) KDM4EMEN1KMT2ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6720287-B2 WHEN AN AROMATIC DICARBOXYLATE IS ENCAPSULATEDTOGETHER WITH THE DIAZONIUM SALT COMPOUND, GENERATION OF PHOTODECOMPOSITION STAIN IS REDUCED AND SHELF LIFE IS IMPROVED FUJI PHOTO FILM CO., LTD. (JP) 2004-04-13 US disclosed
US-20030045426-A1 Heat sensitive recording material and microcapsule solution FUJI PHOTO FILM CO., LTD. 2003-03-06 US disclosed