Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | GGT1 | P19440 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869020 | 0.88 | MAPK1 (0.50) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11622076 | 0.88 | MAPK1 (0.52) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL10573912 | 0.87 | MAPK1 (0.61) | KMT2AHPGDALDH1A1TSHRTDP1 | |
| SCHEMBL5835239 | 0.86 | KDM4E (0.56) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL8436639 | 0.85 | KDM4E (0.63) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL6847069 | 0.85 | MAPK1 (0.50) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL9092886 | 0.84 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL14036097 | 0.84 | KDM4E (0.48) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL2906642 | 0.83 | MAPK1 (0.49) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL27658575 | 0.83 | SLC6A3 (0.62) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822532-B1 | AQUEOUS POLYURETHANE DISPERSION IN THE TREATMENT OF ACNE | COVESTRO DEUTSCHLAND AG (DE) | 2018-09-19 | — | — | EP | claimed |
| EP-2196469-A1 | Conjugates with anti-inflammatory activity | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) | 2010-06-16 | — | — | EP | claimed |
| EP-1261347-B1 | THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING PERIODONTITIS WITH ANTIINFLAMATORY COMPOUNDS | UNIV RUTGERS (US) | 2009-09-30 | — | — | EP | claimed |
| EP-1633771-B1 | MACROLIDE-CONJUGATES WITH ANTI-INFLAMMATORY ACTIVITY | GLAXOSMITHKLINE ZAGREB (HR) | 2009-07-15 | — | — | EP | claimed |
| EP-2070940-A1 | Compounds with anti-inflammatory activity | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) | 2009-06-17 | — | — | EP | claimed |
| EP-1617816-B1 | NANOPARTICULATE MELOXICAN FORMULATIONS | ELAN PHARMA INT LTD (IE) | 2009-05-13 | — | — | EP | claimed |
| EP-1551865-B1 | HYBRID MOLECULES OF MACROLIDES WITH STEROIDAL/NON-STEROIDAL ANTI-INFLAMMATORY MOLECULES | GLAXOSMITHKLINE ZAGREB (HR) | 2009-04-22 | — | — | EP | claimed |
| US-20090048221-A1 | Conjugates with Anti-Inflammatory Activity | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2009-02-19 | — | — | US | claimed |
| EP-1805202-A2 | CONJUGATES WITH ANTI-INFLAMMATORY ACTIVITY | PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) | 2007-07-11 | — | — | EP | claimed |
| EP-1778292-A2 | USE OF CELL-SPECIFIC CONJUGATES FOR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. (HR) | 2007-05-02 | — | — | EP | claimed |
| WO-2006018698-A2 | USE OF CELL-SPECIFIC CONJUGATES FOR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (US) | 2006-02-23 | — | — | WO | claimed |
| US-20060035845-A1 | Use of immune cell specific conjugates for treatment of inflammatory diseases of the gastrointestinal tract | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. | 2006-02-16 | — | — | US | claimed |
| EP-1551865-A2 | HYBRID MOLCULES OF MACROLIDES WITH STEROID/NON-STEROID ANTI-INFLAMMATORY, ANTINEOPLASTIC AND ANTIVIRAL ACTIVE MOLECULES | Pliva - Istrazivacki Institut d.o.o. (HR) | 2005-07-13 | — | — | EP | claimed |
| US-20050080003-A1 | Compounds with anti-inflammatory activity | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2005-04-14 | — | — | US | claimed |
| EP-1521763-A2 | NOVEL NONSTEROIDAL ANTI-INFLAMMATORY SUBSTANCES, COMPOSITIONS AND METHODS FOR THEIR USE | Pliva - Istrazivacki Institut d.o.o. (HR) | 2005-04-13 | — | — | EP | claimed |
| WO-2004094449-A1 | MACROLIDE-CONJUGATES WITH ANTI-INFLAMMATORY ACTIVITY | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (US) | 2004-11-04 | — | — | WO | claimed |
| US-20040097434-A1 | Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use | PLIVA PHARMACEUTICAL INDUSTRY, INCORPORATED | 2004-05-20 | — | — | US | claimed |
| US-20040077612-A1 | Novel compounds, compositions as carriers for steroid/nonsteroid anti-inflammatory; antienoplastic and antiviral active molecules | PLIVA DD (HR) | 2004-04-22 | — | — | US | claimed |
| WO-2004005313-A2 | HYBRID MOLECULES OF MACROLIDES WITH STEROID/NON-STEROID ANTI-INFLAMMATORY, ANTINEOPLASTIC AND ANTIVIRAL ACTIVE MOLECULES | PLIVA - ISTRAZIVACKI INSTITUT D.O.O. (US) | 2004-01-15 | — | — | WO | claimed |
| WO-2004005309-A2 | NOVEL NONSTEROIDAL ANTI-INFLAMMATORY SUBSTANCES, COMPOSITIONS AND METHODS FOR THEIR USE | PLIVA - ISTRAZIVACKI INSTITUT D.O.O. (US) | 2004-01-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080003-A1 | Compounds with anti-inflammatory activity | NOD1, NOD2, TNF | KDM4E 3272/4885KMT2A 4552/4885MEN1 3747/4885 |
| US-20060035845-A1 | Use of immune cell specific conjugates for treatment of inflammatory diseases of the gastrointestinal tract | SI, MALT1, CD4 | KDM4E 1989/4885KMT2A 3252/4885MEN1 4103/4885 |
| US-20090048221-A1 | Conjugates with Anti-Inflammatory Activity | MPO, EPX, NOD1 | KDM4E 2438/4885KMT2A 3277/4885MEN1 4318/4885 |
| US-20040097434-A1 | Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use | PTGS1, IL1B, LTB4R2 | KDM4E 3705/4885KMT2A 4656/4885MEN1 4616/4885 |
| US-20040077612-A1 | Novel compounds, compositions as carriers for steroid/nonsteroid anti-inflammatory; antienoplastic and antiviral active molecules | MALT1, TNF, IL1B | KDM4E 2444/4885KMT2A 4399/4885MEN1 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.