Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.98 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F12 | P00748 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869091 | 1.00 | ADORA2A (0.98) | ADORA2AHPGDCYP2C9F2F12 | |
| SCHEMBL6871467 | 1.00 | ADORA2A (0.98) | ADORA2AHPGDCYP2C9F2F12 | |
| SCHEMBL6867568 | 0.99 | ADORA2A (1.00) | ADORA2AHPGDCYP2C9F2F12 | |
| SCHEMBL6871685 | 0.88 | ADORA2A (0.80) | ADORA2AF2F12PLAU | |
| SCHEMBL7143076 | 0.87 | ADORA2A (0.78) | ADORA2AHPGD | |
| SCHEMBL6873970 | 0.85 | ADORA2A (0.74) | ADORA2AHPGD | |
| SCHEMBL6867372 | 0.84 | ADORA2A (0.74) | ADORA2AF2F12PLAU | |
| SCHEMBL6867145 | 0.84 | ADORA2A (0.71) | ADORA2AHPGD | |
| SCHEMBL6863643 | 0.84 | ADORA2A (0.73) | ADORA2AHPGD | |
| SCHEMBL6868104 | 0.83 | ADORA2A (0.72) | ADORA2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |
| US-6506772-B1 | Pharmaceutically active salts thereof with activity as adenosine receptor ligands are disclosed. These compounds are the adenosine receptor. | HOFFMANN-LA ROCHE INC. | 2003-01-14 | — | — | US | disclosed |