Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.67 |
| ▸ | NMT2 | O60551 | 12/20 | 0.53 |
| ▸ | NMT1 | P30419 | 12/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | BAD | Q92934 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868030 | 0.88 | EDNRA (0.52) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL3603130 | 0.86 | EDNRA (0.70) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL6871391 | 0.86 | NMT2 (0.71) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL6863218 | 0.85 | NMT2 (0.52) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL3612478 | 0.83 | EDNRA (0.73) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL6869508 | 0.83 | NMT2 (0.47) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL3618219 | 0.83 | EDNRA (0.65) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL6869505 | 0.82 | NMT2 (0.49) | EDNRANMT2NMT1ADRB2ADRB1 | |
| SCHEMBL6863935 | 0.81 | NMT2 (0.77) | EDNRANMT2NMT1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL6872183 | 0.81 | NMT2 (0.77) | EDNRANMT2NMT1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| CN-1333770-A | Novel Bicyclic Compounds | BASLIER PHARMACEUTICAL AG (CH) | 2002-01-30 | — | — | CN | disclosed |
| EP-1149094-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037464-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2000-06-29 | — | — | WO | disclosed |