Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 4/20 | 0.77 |
| ▸ | NMT1 | P30419 | 4/20 | 0.77 |
| ▸ | EDNRA | P25101 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869191 | 0.81 | EDNRA (0.67) | NMT2NMT1EDNRAKDM4EADRB2 | |
| SCHEMBL3603130 | 0.80 | EDNRA (0.70) | NMT2NMT1EDNRAMAPTKDM4E | |
| SCHEMBL3612478 | 0.78 | EDNRA (0.73) | NMT2NMT1EDNRAL3MBTL1MAPT | |
| SCHEMBL3618219 | 0.77 | EDNRA (0.65) | NMT2NMT1EDNRAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6872183 | 0.75 | NMT2 (0.77) | NMT2NMT1EDNRAADRB2ADRB1 | |
| SCHEMBL3617915 | 0.75 | EDNRA (0.65) | NMT2NMT1EDNRAKDM4EADRB2 | |
| SCHEMBL5749264 | 0.74 | TDP1 (0.59) | NMT2NMT1L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL3617976 | 0.73 | EDNRA (0.68) | NMT2NMT1EDNRAALDH1A1KDM4E | |
| SCHEMBL5749883 | 0.73 | XDH (0.59) | NMT2NMT1CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL7894363 | 0.73 | EDNRA (0.54) | NMT2NMT1EDNRAADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | claimed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | claimed |
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |