Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 11/20 | 0.47 |
| ▸ | F10 | P00742 | 10/20 | 0.47 |
| ▸ | F2 | P00734 | 10/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.47 |
| ▸ | F3 | P13726 | 4/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883278 | 0.90 | F7 (0.58) | F7F10F2PRSS1F3 | |
| SCHEMBL5882514 | 0.87 | F10 (0.43) | F7F10F2PRSS1F3 | |
| SCHEMBL5883181 | 0.83 | MAOB (0.47) | PPARGSMPD1SGMS2 | |
| SCHEMBL7414799 | 0.81 | F10 (0.50) | F7F10F2PRSS1F3 | |
| SCHEMBL5883027 | 0.79 | F10 (0.47) | F7F10F2PRSS1F3 | |
| SCHEMBL5883981 | 0.78 | F7 (0.53) | F7F10F2PRSS1F3 | |
| SCHEMBL7410198 | 0.77 | F10 (0.45) | F7F10F2PRSS1F3 | |
| SCHEMBL5883376 | 0.76 | MAOB (0.47) | F7F10F2PRSS1F3 | |
| SCHEMBL7139369 | 0.76 | F7 (0.48) | F7F10F2PRSS1F3 | |
| SCHEMBL7139374 | 0.76 | F7 (0.48) | F7F10F2PRSS1F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-B1 | PHENYLGLYCINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-08-25 | — | — | EP | disclosed |
| EP-1149069-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |