Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 15/20 | 0.41 |
| ▸ | NMT1 | P30419 | 15/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863131 | 0.80 | NMT2 (0.41) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL29958638 | 0.78 | EDNRA (0.64) | NMT2NMT1EDNRA | |
| SCHEMBL6869191 | 0.77 | EDNRA (0.67) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6872423 | 0.77 | NMT2 (0.42) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL9206123 | 0.77 | KDM4E (0.40) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6868030 | 0.76 | EDNRA (0.52) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6871609 | 0.75 | NMT2 (0.49) | NMT2NMT1 | |
| SCHEMBL6871391 | 0.74 | NMT2 (0.71) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL6863218 | 0.74 | NMT2 (0.52) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL7890729 | 0.74 | NMT2 (0.42) | NMT2NMT1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| EP-1149094-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037464-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2000-06-29 | — | — | WO | disclosed |