SCHEMBL9682575

SCHEMBL9682575

Cc1nc(F)nc(N)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
NOS1 P29475 1/20 0.31
TLR8 Q9NR97 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13754208 0.82 CYP1A2 (0.32) IDO1LMNA
SCHEMBL19754271 0.75 IDO1 (0.41) IDO1TLR8LMNA
SCHEMBL17342568 0.75 TLR8 (0.44) IDO1TLR8LMNA
SCHEMBL9680756 0.75 KHK (0.32)
SCHEMBL1143207 0.75 IDO1 (0.41) IDO1TLR8LMNA
SCHEMBL24820952 0.75 NOS1 (0.33) NOS1LMNA
SCHEMBL19864844 0.75 LMNA (0.37) IDO1NOS1LMNA
SCHEMBL8947552 0.75
SCHEMBL9336420 0.75 MEN1 (0.31)
SCHEMBL6869641 0.73 IDO1 (0.39) IDO1TLR8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170369721-A1 INK COMPOSITION, INK SET, AND RECORDING METHOD SEIKO EPSON CORPORATION (JP) 2017-12-28 US disclosed
US-5128455-A WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-07 US disclosed
US-4948879-A Monoazo compounds containing a fiber-reactive group and an oxazolopyridone or oxazinopyridone coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-14 US disclosed
EP-0316778-A2 2-Hydroxy-pyridone azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170369721-A1 INK COMPOSITION, INK SET, AND RECORDING METHOD IK, SETDB1, SET IDO1 192/4885NOS1 919/4885TLR8 4118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.