Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12088667 | 0.92 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL12088447 | 0.89 | NR5A1 (0.55) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL1667493 | 0.87 | NR5A1 (0.58) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL9270936 | 0.87 | NR5A1 (0.58) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL6872219 | 0.87 | NR5A1 (0.58) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL15018829 | 0.87 | NR5A1 (0.58) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL27792511 | 0.84 | LMNA (0.50) | LMNAL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2559226 | 0.83 | NQO1 (0.61) | LMNAL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL909957 | 0.83 | LMNA (0.58) | LMNAL3MBTL1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL810802 | 0.83 | ALDH1A1 (0.47) | LMNAL3MBTL1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101068797-A | Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof | MITSUBISHI PHARMA CORP (JP) | 2007-11-07 | — | — | CN | disclosed |
| EP-1390337-A1 | PRECURSORS FOR KETONES AND ALDEHYDES | Givaudan SA (CH) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002096850-A1 | PRECURSORS FOR KETONES AND ALDEHYDES | GIVAUDAN SA (CH) | 2002-12-05 | — | — | WO | disclosed |