Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.45 |
| ▸ | VNN1 | O95497 | 5/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870280 | 0.84 | ADORA2A (0.53) | ADORA2AABL1BCR | |
| SCHEMBL6867345 | 0.82 | ADORA2A (0.63) | ADORA2A | |
| SCHEMBL6872157 | 0.82 | ADORA2A (0.50) | ADORA2A | |
| SCHEMBL6863814 | 0.80 | ADORA2A (0.67) | ADORA2AABL1BCR | |
| SCHEMBL6871877 | 0.80 | ADORA2A (0.48) | ADORA2A | |
| SCHEMBL6870030 | 0.79 | ADORA2A (0.66) | ADORA2AABL1BCR | |
| SCHEMBL6863267 | 0.79 | ADORA2A (0.66) | ADORA2AABL1BCR | |
| SCHEMBL6863682 | 0.79 | ADORA2A (0.66) | ADORA2AABL1BCR | |
| SCHEMBL6869364 | 0.79 | ADORA2A (0.70) | ADORA2A | |
| SCHEMBL6870405 | 0.79 | ADORA2A (0.60) | ADORA2AABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |
| US-6506772-B1 | Pharmaceutically active salts thereof with activity as adenosine receptor ligands are disclosed. These compounds are the adenosine receptor. | HOFFMANN-LA ROCHE INC. | 2003-01-14 | — | — | US | disclosed |