Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984759 | 0.80 | MAPT (0.53) | HSP90AA1OPRK1KMT2AALDH1A1MAPK1 | |
| SCHEMBL1461144 | 0.77 | KMT2A (0.67) | IDO1HSP90AA1HSP90AB1PSMB5EP300 | |
| SCHEMBL27300401 | 0.74 | CYP1A2 (0.49) | IDO1HSP90AA1HSP90AB1PSMB5PLAU | |
| SCHEMBL6869500 | 0.73 | MAPT (0.54) | HSP90AA1OPRK1KMT2AALDH1A1MAPK1 | |
| SCHEMBL11002658 | 0.72 | PLAU (0.38) | IDO1HSP90AA1HSP90AB1ALDH1A1HPGD | |
| SCHEMBL17543647 | 0.72 | MAPT (0.40) | IDO1HSP90AA1OPRK1KMT2AALDH1A1 | |
| SCHEMBL10705051 | 0.70 | CTSB (0.68) | HSP90AA1OPRK1KMT2AALDH1A1HPGD | |
| SCHEMBL14905844 | 0.70 | — | — | |
| SCHEMBL1332804 | 0.70 | — | — | |
| SCHEMBL30427153 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818653-B1 | 7-THIOCYANO SUBSTITUENT; REACTING 6,7-DIHALO-5,8-QUINOLINEDIONE AND ANILINE DERIVATIVE; AMINATION | IL JIN COPPER FOIL CORP. (KR) | 2004-11-16 | — | — | US | disclosed |
| EP-1175403-A4 | 6,7-DISUBSTITUTED-5,8-QUINOLINEDIONE DERIVATIVES AS AN ANTIFUNGAL AGENT | IL JIN COPPER FOIL CORP (KR) | 2002-06-12 | — | — | EP | disclosed |
| EP-1175403-A1 | 6,7-DISUBSTITUTED-5,8-QUINOLINEDIONE DERIVATIVES AS AN ANTIFUNGAL AGENT | Il Jin Copper Foil Corp. (KR) | 2002-01-30 | — | — | EP | disclosed |
| WO-2001012605-A1 | 6,7-DISUBSTITUTED-5,8-QUINOLINEDIONE DERIVATIVES AS AN ANTIFUNGAL AGENT | IL JIN COPPER FOIL CORP. (KR) | 2001-02-22 | — | — | WO | disclosed |