Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876928 | 0.82 | MAPT (0.57) | MAPTTDP1L3MBTL1KDM4ENPC1 | |
| SCHEMBL28191903 | 0.79 | ALDH1A1 (0.36) | MAPTTDP1L3MBTL1KDM4ENPC1 | |
| SCHEMBL3984759 | 0.76 | MAPT (0.53) | MAPTTDP1KDM4EALDH1A1KMT2A | |
| SCHEMBL6869752 | 0.73 | IDO1 (0.50) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL12834067 | 0.72 | KDM4E (0.40) | MAPTTDP1L3MBTL1KDM4ENPC1 | |
| SCHEMBL105461 | 0.70 | L3MBTL1 (1.00) | MAPTTDP1L3MBTL1KDM4ENPC1 | |
| SCHEMBL29624594 | 0.70 | L3MBTL1 (1.00) | MAPTTDP1L3MBTL1KDM4ENPC1 | |
| SCHEMBL10705051 | 0.70 | CTSB (0.68) | MAPTTDP1L3MBTL1KDM4ENPC1 | |
| SCHEMBL31157828 | 0.69 | L3MBTL1 (0.97) | MAPTTDP1L3MBTL1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL6865586 | 0.69 | L3MBTL1 (0.97) | MAPTTDP1L3MBTL1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818653-B1 | 7-THIOCYANO SUBSTITUENT; REACTING 6,7-DIHALO-5,8-QUINOLINEDIONE AND ANILINE DERIVATIVE; AMINATION | IL JIN COPPER FOIL CORP. (KR) | 2004-11-16 | — | — | US | disclosed |
| EP-1175403-A4 | 6,7-DISUBSTITUTED-5,8-QUINOLINEDIONE DERIVATIVES AS AN ANTIFUNGAL AGENT | IL JIN COPPER FOIL CORP (KR) | 2002-06-12 | — | — | EP | disclosed |
| EP-1175403-A1 | 6,7-DISUBSTITUTED-5,8-QUINOLINEDIONE DERIVATIVES AS AN ANTIFUNGAL AGENT | Il Jin Copper Foil Corp. (KR) | 2002-01-30 | — | — | EP | disclosed |
| WO-2001012605-A1 | 6,7-DISUBSTITUTED-5,8-QUINOLINEDIONE DERIVATIVES AS AN ANTIFUNGAL AGENT | IL JIN COPPER FOIL CORP. (KR) | 2001-02-22 | — | — | WO | disclosed |