Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863514 | 0.90 | ADORA2A (0.58) | ADORA2A | |
| SCHEMBL6863745 | 0.89 | ADORA2A (0.57) | ADORA2ATSHRLMNA | |
| SCHEMBL6870021 | 0.89 | ADORA2A (0.83) | ADORA2AALDH1A1 | |
| SCHEMBL6873024 | 0.89 | ADORA2A (0.75) | ADORA2AALDH1A1KMT2ALMNA | |
| SCHEMBL6869908 | 0.88 | ADORA2A (0.80) | ADORA2A | |
| SCHEMBL6872091 | 0.87 | ADORA2A (0.82) | ADORA2A | |
| SCHEMBL6870373 | 0.86 | ADORA2A (0.54) | ADORA2AALDH1A1TSHRGAAKMT2A | |
| SCHEMBL6869273 | 0.85 | ADORA2A (0.56) | ADORA2A | |
| SCHEMBL6867947 | 0.85 | ADORA2A (0.74) | ADORA2A | |
| SCHEMBL6870569 | 0.84 | ADORA2A (0.73) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |