Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.37 |
| ▸ | FABP7 | O15540 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275884 | 0.75 | CA1 (0.50) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL31501939 | 0.74 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL456018 | 0.74 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL2730698 | 0.73 | CA1 (0.57) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL1703198 | 0.72 | CA1 (0.47) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL6649914 | 0.71 | BCHE (0.32) | HTR2AACHEBCHEGPR3POLB | |
| SCHEMBL633764 | 0.71 | HTR2A (0.58) | CA1CA2HTR2AACHEBCHE | |
| SCHEMBL16485220 | 0.70 | CA1 (0.46) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL21800941 | 0.70 | CA1 (0.69) | CA1CA2HTR2AKMT2AFABP5 | |
| SCHEMBL4992955 | 0.70 | CA1 (0.53) | CA1CA2HTR2AKMT2AFABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6822109-B2 | TRIHYDROCARBYLSILYLATION; ADDITION POLYMERIZATION OF OLEFINS | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2004-11-23 | — | — | US | disclosed |