Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.42 |
| ▸ | F7 | P08709 | 9/20 | 0.42 |
| ▸ | F3 | P13726 | 9/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.42 |
| ▸ | F2 | P00734 | 7/20 | 0.42 |
| ▸ | F10 | P00742 | 8/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | HAT1 | O14929 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882857 | 0.88 | PRSS1 (0.49) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL7421141 | 0.83 | PRSS1 (0.50) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL6870487 | 0.83 | GPR119 (0.56) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL5883650 | 0.78 | PRSS1 (0.53) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL5882153 | 0.78 | PRSS1 (0.59) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL4101596 | 0.76 | GPR119 (0.53) | GPR119EPHX2HRH3 | |
| SCHEMBL5882560 | 0.76 | PRSS1 (0.61) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL5883682 | 0.75 | PRSS1 (0.61) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL5883162 | 0.74 | F10 (0.55) | PRSS1PRSS2F7F3PRSS3 | |
| SCHEMBL5882740 | 0.74 | PRSS1 (0.73) | PRSS1PRSS2F7F3PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149069-B1 | PHENYLGLYCINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-08-25 | — | — | EP | disclosed |