Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647993 | 0.91 | TSHR (0.40) | TSHRALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL8984823 | 0.91 | CYP2C19 (0.35) | TSHRALDH1A1CYP2C19KMT2AMEN1 | |
| Bromide SCHEMBL28263939 | 0.90 | TSHR (0.52) | TSHRALDH1A1CYP2C19ADH1BADH1C | |
| Iodide SCHEMBL28868954 | 0.90 | TSHR (0.52) | TSHRALDH1A1CYP2C19ADH1BADH1C | |
| SCHEMBL28735575 | 0.83 | TSHR (0.39) | TSHRALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL19669 | 0.82 | CA12 (0.48) | TSHRALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL27591294 | 0.80 | CA12 (0.46) | TSHRALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL8206827 | 0.80 | CA12 (0.48) | TSHRALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL18329453 | 0.80 | TSHR (0.44) | TSHRALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL704639 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030071-A1 | HYDRIDOSILAPYRROLES, HYDRIDOSILAAZAPYRROLES, THIASILACYCLOPENTANES, METHOD FOR PREPARATION THEREOF, AND REACTION PRODUCTS THEREFROM | GELEST, INC. | 2018-02-01 | — | — | US | disclosed |
| EP-1829925-B1 | RUBBER COMPOSITION, METHOD FOR PRODUCING SAME AND TIRE | BRIDGESTONE CORP (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20090124742-A1 | Rubber Composition, Method for Producing Same and Tire | BRIDGESTONE CORPORATION (JP) | 2009-05-14 | — | — | US | disclosed |
| EP-1829925-A1 | RUBBER COMPOSITION, METHOD FOR PRODUCING SAME AND TIRE | Bridgestone Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030071-A1 | HYDRIDOSILAPYRROLES, HYDRIDOSILAAZAPYRROLES, THIASILACYCLOPENTANES, METHOD FOR PREPARATION THEREOF, AND REACTION PRODUCTS THEREFROM | HAAO, TST, TH | TSHR 352/4885ALDH1A1 1281/4885CYP2C19 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.