Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | ADH5 | P11766 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850622 | 1.00 | MAPT (0.53) | MAPTMEN1KMT2AKDM4EMITF | |
| SCHEMBL6850615 | 1.00 | MAPT (0.53) | MAPTMEN1KMT2AKDM4EMITF | |
| SCHEMBL6852114 | 0.81 | ENPP2 (0.54) | MAPTMEN1KMT2AKDM4EMITF | |
| SCHEMBL6876975 | 0.81 | ENPP2 (0.54) | MAPTMEN1KMT2AKDM4EMITF | |
| SCHEMBL6852438 | 0.81 | QPCT (0.41) | MAPTMEN1KMT2AKDM4EMITF | |
| SCHEMBL6852443 | 0.81 | QPCT (0.41) | MAPTMEN1KMT2AKDM4EMITF | |
| SCHEMBL6852433 | 0.81 | QPCT (0.41) | MAPTMEN1KMT2AKDM4EMITF | |
| SCHEMBL7290730 | 0.77 | CYP11B1 (0.60) | MAPTMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL7290735 | 0.77 | CYP11B1 (0.60) | MAPTMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL7290725 | 0.77 | CYP11B1 (0.60) | MAPTMEN1KMT2ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |