Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852438 | 1.00 | QPCT (0.41) | QPCTCYP1A2CYP2C9KMT2AKDM4E | |
| SCHEMBL6852443 | 1.00 | QPCT (0.41) | QPCTCYP1A2CYP2C9KMT2AKDM4E | |
| SCHEMBL6850622 | 0.81 | MAPT (0.53) | CYP1A2CYP2C9KMT2AKDM4EMEN1 | |
| SCHEMBL6870710 | 0.81 | MAPT (0.53) | CYP1A2CYP2C9KMT2AKDM4EMEN1 | |
| SCHEMBL6850615 | 0.81 | MAPT (0.53) | CYP1A2CYP2C9KMT2AKDM4EMEN1 | |
| SCHEMBL6877238 | 0.74 | KDM4E (0.57) | CYP1A2CYP2C9KMT2AKDM4EMEN1 | |
| SCHEMBL6847715 | 0.74 | NOTUM (0.51) | — | |
| SCHEMBL6877239 | 0.74 | KDM4E (0.57) | CYP1A2CYP2C9KMT2AKDM4EMEN1 | |
| SCHEMBL6847717 | 0.74 | NOTUM (0.51) | — | |
| SCHEMBL6877242 | 0.74 | KDM4E (0.57) | CYP1A2CYP2C9KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |