Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | PYGM | P11217 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12598788 | 0.78 | CXCR4 (0.64) | KDM4EALDH1A1ALOX15TSHRHTT | |
| SCHEMBL2084334 | 0.78 | VDR (0.50) | KDM4EALDH1A1ALOX15TSHRHTT | |
| SCHEMBL5550219 | 0.77 | HSD17B10 (0.47) | KDM4EALDH1A1ALOX15TSHRHTT | |
| SCHEMBL29205391 | 0.75 | HRH1 (0.54) | KDM4EALDH1A1ALOX15TSHRHTT | |
| SCHEMBL30281772 | 0.75 | HRH1 (0.54) | KDM4EALDH1A1ALOX15TSHRHTT | |
| SCHEMBL20448743 | 0.72 | SMN1; SMN2 (0.55) | KDM4EALDH1A1ALOX15TSHRHTT | |
| SCHEMBL6873837 | 0.71 | LMNA (0.64) | KDM4EALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL19888989 | 0.70 | RPS6KA2 (0.52) | KDM4EALDH1A1ALOX15TSHRHTT | |
| SCHEMBL2082545 | 0.69 | TDP1 (0.66) | KDM4EALDH1A1ALOX15TSHRHTT | |
| SCHEMBL9671309 | 0.69 | BRD4 (0.55) | KDM4EALDH1A1HTTHSD17B10HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| EP-1149094-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037464-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2000-06-29 | — | — | WO | disclosed |