Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | ESRRB | O95718 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687077 | 1.00 | BLM (0.40) | BLMESRRGCA2MTORKDM4E | |
| SCHEMBL4148049 | 0.73 | BLM (0.53) | BLMESRRGCA2MTORESR1 | |
| SCHEMBL3595900 | 0.72 | MEN1 (0.43) | MEN1KMT2AALDH1A1CYP3A4HTT | |
| SCHEMBL9387125 | 0.71 | KMT2A (0.49) | BLMESRRGCA2KDM4EF13A1 | |
| SCHEMBL4147783 | 0.70 | ESRRG (0.49) | BLMESRRGCA2KDM4EF13A1 | |
| SCHEMBL4297210 | 0.70 | KDM4E (0.42) | BLMESRRGCA2KDM4EF13A1 | |
| SCHEMBL4297214 | 0.70 | KDM4E (0.42) | BLMESRRGCA2KDM4EF13A1 | |
| SCHEMBL20134718 | 0.69 | CA2 (0.31) | CA2 | |
| SCHEMBL20134717 | 0.69 | CA2 (0.31) | CA2 | |
| SCHEMBL31563005 | 0.68 | BLM (0.69) | BLMESRRGCA2MTORKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622860-B1 | AMINO-PROPANOL DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE RECEPTOR MODULATORs | NOVARTIS AG (CH) | 2012-02-29 | — | — | EP | disclosed |