Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20134718 | 1.00 | CA2 (0.31) | CA2MAPK1AKR1B1SLC1A3SLC1A2 | |
| SCHEMBL15796199 | 0.76 | SMPD1 (0.38) | — | |
| SCHEMBL15670967 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL15240897 | 0.72 | CYP2D6 (0.30) | — | |
| SCHEMBL687076 | 0.69 | BLM (0.40) | CA2 | |
| SCHEMBL687077 | 0.69 | BLM (0.40) | CA2 | |
| SCHEMBL2876460 | 0.69 | — | — | |
| SCHEMBL14778273 | 0.69 | — | — | |
| SCHEMBL17363044 | 0.68 | MEN1 (0.30) | — | |
| SCHEMBL3595900 | 0.67 | MEN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321265-A1 | 4,6-DIAMINO-PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS AND THEIR UTILISATION AS MODULATORS OF TOLL-LIKE RECEPTORS | Gilead Sciences, Inc. (US) | 2018-05-16 | — | — | EP | disclosed |