Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 12/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 8/20 | 0.51 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870789 | 1.00 | DYRK1A (0.51) | DYRK1ADYRK1BDYRK2MKNK1MKNK2 | |
| SCHEMBL6870784 | 1.00 | DYRK1A (0.51) | DYRK1ADYRK1BDYRK2MKNK1MKNK2 | |
| SCHEMBL6880197 | 0.84 | MMP12 (0.39) | CYP3A4ERN1 | |
| SCHEMBL6851843 | 0.84 | MMP12 (0.39) | CYP3A4ERN1 | |
| SCHEMBL6880201 | 0.84 | MMP12 (0.39) | CYP3A4ERN1 | |
| SCHEMBL6852045 | 0.83 | DYRK1A (0.54) | DYRK1ADYRK1BDYRK2CYP2A6CYP3A4 | |
| SCHEMBL6852049 | 0.83 | DYRK1A (0.54) | DYRK1ADYRK1BDYRK2CYP2A6CYP3A4 | |
| SCHEMBL6852674 | 0.83 | ERN1 (0.31) | ERN1 | |
| SCHEMBL6852666 | 0.83 | ERN1 (0.31) | ERN1 | |
| SCHEMBL6852667 | 0.83 | ERN1 (0.31) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |