Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.44 |
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | NMT2 | O60551 | 5/20 | 0.41 |
| ▸ | NMT1 | P30419 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871393 | 0.89 | MAOA (0.44) | MAOAMAOBACHENMT2NMT1 | |
| SCHEMBL3478595 | 0.88 | MAOA (0.48) | MAOAMAOBACHENMT2NMT1 | |
| SCHEMBL6871614 | 0.83 | NMT2 (0.57) | MAOAMAOBACHENMT2NMT1 | |
| SCHEMBL6869562 | 0.81 | MAOA (0.50) | MAOAMAOBACHENMT2NMT1 | |
| SCHEMBL6863650 | 0.79 | MAOA (0.44) | MAOAMAOBACHENMT2NMT1 | |
| SCHEMBL3470262 | 0.78 | NMT2 (0.68) | NMT2NMT1 | |
| SCHEMBL6870895 | 0.76 | NMT2 (0.39) | NMT2NMT1 | |
| SCHEMBL3470217 | 0.74 | NMT2 (0.42) | NMT2NMT1 | |
| SCHEMBL7889774 | 0.74 | NMT2 (0.38) | NMT2NMT1 | |
| SCHEMBL3472648 | 0.74 | NMT2 (0.70) | NMT2NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149094-B1 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6376491-B1 | BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS | BASILEA PHARMACEUTICA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| EP-1149094-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000037464-A2 | 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2000-06-29 | — | — | WO | disclosed |