Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5987512 | 0.87 | TYMP (0.41) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL7743648 | 0.86 | ADORA2A (0.40) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6298549 | 0.85 | ADORA2A (0.53) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL8306794 | 0.79 | ADORA3 (0.49) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL11701245 | 0.78 | ADORA2A (0.53) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL11703712 | 0.78 | ADORA2A (0.54) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL5989031 | 0.78 | ADORA3 (0.38) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL3409898 | 0.77 | ADORA2A (0.53) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL258946 | 0.77 | ADORA3 (0.52) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL259555 | 0.76 | ADORA3 (0.47) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404338-A1 | ADENOSINE ANALOGUES FOR THE TREATMENT OF THE INSULIN RESISTANCE SYNDROME AND DIABETES | Aventis Pharma Deutschland GmbH (DE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002092093-A1 | ADENOSINE ANALOGUES FOR THE TREATMENT OF THE INSULIN RESISTANCE SYNDROME AND DIABETES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-11-21 | — | — | WO | disclosed |
| WO-2000023447-A1 | ADENOSINE ANALOGUES HAVING ANTIHYPERTENSIVE, CARDIOPROTECTIVE, ANTI-ISCHEMIC ANTILIPOLYTIC PROPERTIES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 2000-04-27 | — | — | WO | disclosed |